Similarities between a dipeptide hydrolase from brush-border and cytosol fractions of guinea-pig intestinal mucosa.
نویسندگان
چکیده
A dipeptide hydrolase from the brush border of guinea-pig intestinal mucosa was purified. The enzyme resembles another dipeptide hydrolase isolated from the cytosol fraction of intestinal mucosa. Studies on the binding of cytosol peptide hydrolase to brush-border membranes indicate that the enzyme found in the brush border may be a cytoplasmic contaminant.
منابع مشابه
Relationship between peptide hydrolases in brush-border and cytosol fractions of guinea-pig intestinal mucosa.
Studies on the terminal stages of mammalian protein digestion, which is thought to involve the hydrolysis of peptides containing from two to six amino acids (Crampton et al., 1971), have been hampered by the fact that the enzymes involved appear to be distributed between two fractions of the mucosal cells (enterocytes), the brushborder and cytosol fractions (Peters, 1970). Some controversy exis...
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ورودعنوان ژورنال:
- The Biochemical journal
دوره 159 3 شماره
صفحات -
تاریخ انتشار 1976